I prefer non-drug life extension.
Unfortunately preferences in the real world don't matter, facts do. There won't be any considerable life extension without drugs and heavy medical interventions*. Personally, I do prefer non-drug life extension myself! Heck, personally I'd prefer waking up tomorrow and staying young forver; but I realise that's wishful thinking.
In the end it comes down to a combination, which will be heavily biased towards drugs and biomedical interventions once they get here, but, to repeat, there will never be considerable life extension without them.
(additionally I find the distinction between drugs and "supplements" quite funny, ironically American supplements tend to be drugs in Europe - the distinction between drug and supplement is completely arbitrary)
*this is a consensus statement (both in this forum and within the biogerontology community), as always the burden of proof lies on other people to refute consensus.
If you avoid "mainstream" medical care you can expect a moderately fast and painful demise and a definitely shortened life span.
Really? There are many communities of people throughout the world that avoid mainstream westernized medicine and have some of the longest current lifespans.
Really; while there are
some communities (and in absolute numbers you could say "many") who have fine life spans
most w/o westernised medicine don't. Those people drop dead from simple infectious disease or worse. Furthermore, I call this the fallacy of "no fitting comparison", after all, how can you know their life span wouldn't increase if they had access to better therapy? Populations should be only compared to themselves.
Medicines that work come at a cost
Yeah...death. Kind of makes you rethink the term "works" in regard to these drugs. Yes, Uncle Fred had no more arthritis pain because of Drug X. It WORKED great. Unfortunately, he's now dead because of it. So much for Uncle Fred's plans for life extension.
That's what I mean when I say sensatioanlism. FDA regulation is so god damn strict, it's incredible. No drug gets approved unless it shows solid benefits including decreased mortality also known as extended life span! Oh, and they get
pulled if extremely rare but nonetheless severe side-effects are recognised. (yes, sometimes the system fails, and big business knows how to fake and fudge data but that's the exception)
but sensationalist reporting won't help
Hmmm...as opposed to the sensationalist reporting about the impending DOOM of the H1N1 virus that has been in the media around the clock for months and months. That is the epitome of sensationalism. Do you honestly think that vaccine manufacturers don't encourage such sensationalistic media coverage. They certainly do but it's irrelevant and offtopic, medical consensus is not generated by the mainstream media (which is very good at spreading disinformation).
Believe me, sensationalism is very much a part of the modus operandi of mainstream medicine. Did you just confuse mainstream media and "mainstream medicine"? (or did you do this on purpose?) Well, you could have gotten your information from MEDLINE, the cdc, science bloggers, doctors...
You can of course question how these numbers have been found out but not just by your every day experience. How will you know whether the deaths you know from are not iatrogenic? Those cases have the severest consequences for the involved doctors or hospitals, so it's not going to be a normal diagnosis by the ones who are responsible.
Or how will you know that if chemotherapy didn't kill them the cancer wouldn't have killed 'em much earlier and ? Yes, there are many shortcomings to both sides of the equation. But this problem is especially glaring w/ cancer therapy.
Strange alternative between quality and quantity of life (and may be you should only write the first word of the expression "LIFE extension" in capital letters) because no one wants to extend a life which is full of pain, suffering and misery. Quality and quantity of life are two different sides of the same coin and as long as the life extension movement will not see the deeper unity of these basic aspects there cannot be any substantial progress.
This is a misconception which I have refuted quite often. I can understand how this misconception arises, but believe me, it's a complete non-issue. To sum up:
Let's define quality of life (QOL) as "lack of disease and pain (lack of morbidity)". Now, keep in mind that mortality is a function of preceeding morbidity which is a function of biologic age. You cannot extend maximal life span considerably without slowing biological aging, thus without decreasing morbidity and improving QOL. And if you could such a therapy would never get approved.
While I don't mind refuting the understandable
Tithonus error for the Nth time, I don't know how this is related to this thread? Do you imply that drugs do not improve quality of life? If yes, are you serious? Have you read the literature? Quality of life is one of the most important secondary outcomes and in some cases the major outcomes: hospice, pain therapy, antiemetics were (as cynical as it is) some of the greatest advances we made in cancer therapy. What do they do? Yes, they increase quality of life!
The same can be said about any single disease modifying drug: they all automatically improve QOL by slowing the disease.
Some outstanding points have been raised. There are definitely too many deaths caused by modern medicine, but cut the cranky sensationalism guys; especially the 'us vs them' mentality.
Edited by kismet, 21 December 2009 - 04:14 PM.