Help
Bookmark
Del.icio.us
Digg
Email
Facebook
Google
Mixx
Reddit
StumbleUpon
Hey guys,
I wonder if you'd recommend LEF's - "Life Extension Mix"
http://www.lef.org/n.../item00764.html
By the way - - appearently there are two versions for this product (this one's cheaper):
http://www.lef.org/n.../item00634.html
Still, I didn't understand why. What's the difference between them ?
I'm currently taking Pharmanex's Lifepak which seems to be quite ok, although LE-mix seems better.
Anyway, is this product recommended ?
Thanks
Daniel S.
This forum section is sponsored by:
LEF's - LIFE EXTENSION MIX - - What do you think?
Rate Topic:
#0 sponsored ad
#2
Posted 28 January 2005 - 04:31 PM
inarchunite said:
I wonder if you'd recommend LEF's - "Life Extension Mix"
http://www.lef.org/n.../item00764.html
http://www.lef.org/n.../item00764.html
LEF makes very high-quality supplements. However, I'm afraid that I have to quibble with the formulation of many of them. The LEF mix contains many of the hazards common to multivitamins: enough retinol (preformed vitamin A) to roughly double your risk of fracture, unbalanced alpha-tocopherol levels high enough to drive out other E vitamers and increase your risk of all-cause mortality; high-dose niacinamide, which life extensionists should probably avoid due to the potential issue of niacinamide’s nullification of the potential anti-aging effects of sirtuins; hazardous (>20:1) zinc-to-copper ratio; putting green tea extract into the mix, even though green tea and its extracts inhibit absorption of various minerals; inclusion of a variety of ingredients (Such as sylimarin) with no proven safety or efficacy in normal, healthy humans; a dose of lycopene (3 mg) far below the 14-18 mg present in the diets of the high-quintile of the population, established by epidemiology for reduced risk of a variety of diseases; other, minor issues.
AOR has Essential Mix, a powdered multi that solves all of these problems; forthcoming basic and advanced encapsulated multis will also cover these issues. The advanced formulation, Ortho•Core, includes key phytochemicals at doses backed for health benefits in normal, healthy humans, along with detoxification enzyme substrates, and will be available in Canada shortly and in the USA about a month thereafter; watch the AOR website for news. The formulation has been finalized (apologies for the formatting: the forum software won't accept either spaces or manual tabs):
SUPPLEMENT FACTS:
Serving Sizes: 1 Capsule 9 Capsules %DRI
Phytonutrient Complex
Calcium D-Glucarate ………………………………….. 1.6 mg 15 mg *
Chlorophyllin Complex………………………………… 33 mg 300 mg *
Trans-resveratrol (Chirally Pure)………………………. 200 mcg 1.8 mg *
Indole-3-Carbinol (I3C)………………………………… 2 mg 20 mg *
Sulforaphane ………………………………………….. 789 mcg 7.1 mg *
Vitamins
Vitamin A Complex
Retinol (palmitate)……………………………….. 17 mcg 56 IU 150 mcg 500 IU 16.70%
Natural-Source Mixed Carotenoids:
Alpha-carotene……………………………… 178 mcg 148 IU 1.6 mg 1332 IU 44.4%
Beta-carotene………………………………. 666 mcg 1110 IU 6.0 mg 9990 IU 333%
Cryptoxanthin………………………………. 3 mcg 3 IU 30 mcg 25 IU 0.8%
Lutein………………………………………… 744 mcg 6.7 mg *
Lycopene……………………………………. 2 mg 18 mg *
Zeaxathin……………………………………. 61 mcg 545 mcg *
Vitamin B Complex
B1 (Thiamine) …………………………………... 1 mg 9 mg 750%
B2 (Riboflavin) ………………………………….. 278 mcg 2.5 mg 192%
B3 (Niacin (as 144 mg Inositol Hexanicotinate))… 13 mg 115 mg 718%
B5 (d-Ca Pantothenate)………………………….. 11 mg 100 mg 2000%
B6 (Pyridoxine)…………………………………… 3 mg 25 mg 1470%
B12 (Cyanocobalamin)…………………………… 2.6 mcg 24 mcg 1000%
Folic Acid…………………………………………. 89 mcg 800 mcg 400%
Biotin……………………………………………… 33 mcg 300 mcg 1000%
Pyrroloquinoline quinone (PQQ)………………… 3.3 mcg 30 mcg *
Choline (from Bitartrate 500 mg)………………… 22 mg 200 mg 36%
Inositol (from Inositol, Inositol Hexanicotinate)…… 11 mg 100 mg *
Vitamin C Complex
Vitamin C (Magnesium Ascorbate)………………. 13 mg 120 mg 133%
Mixed Citrus Bioflavonoids………………………. 11 mg 100 mg *
Quercetin………………………………………… 7 mg 65 mg *
Vitamin D3 (Cholecalciferol) ………………………….. 2.7 mcg 111 IU 25 mcg 1000 IU 167%
Vitamin E Complex ……………………………………. 11 mg 100 mg *
Tocopherols: 10 mg 90 mg
alpha-tocopherol …………………………… 1.3 mg 2 IU 12 mg 18 IU 80%
beta-tocopherol …………………………….. 0.9 mg 8 mg *
gamma-tocopherol………………………….. 6 mg 52 mg *
delta-tocopherol…………………………….. 1.9 mg 17 mg *
Tocotrienols: 1 mg 10 mg *
alpha-tocotrienol …………………………… 333 mcg 3 mg *
beta-tocotrienol …………………………….. 11 mg 0.1 mg *
gamma-tocotrienol …………………………. 667 mg 6 mg *
delta-tocotrienol…………………………….. 144 mg 1.3 mg *
Vitamin K2 (As Menatetrenone (MK-4))……………….. 56 mcg 500 mcg 416%
Minerals
Boron (Citrate)…………………………………………. 200 mcg 1.8 mg *
Calcium (Citrate-Malate, D-Glucarate)………………… 33 mg 300 mg 30%
Chromium (Picolinate)………………………………….. 11 mcg 100 mcg *
Copper (Citrate)………………………………………… 167 mg 1.5 mg 167%
Iodine (Potassium Iodide)……………………………… 17 mcg 150 mcg 100%
Lithium (Orotate)……………………………………….. 111 mcg 1000 mcg *
Magnesium (Citrate, Aspartate,
Oxide, Ascorbate, Chlorophyllin)……………… 23 mg 210 mg 50%
Manganese (Glycinate)………………………………… 256 mcg 2.3 mg 100%
Molybdenum (Na Molybdate) ………………………… 5 mcg 45 mcg 100%
Selenium (Se-Methylselenocysteine) ………………….. 22 mcg 200 mcg 364%
Silicon (Na Metasilicate)……………………………….. 5.5 mg 50 mg *
Strontium (Citrate)……………………………………… 167 mcg 1.5 mg *
Vanadium (Citrate)……………………………………... 2 mcg 18 mcg *
Zinc (Citrate)…………………………………………… 1 mg 11 mg 100%
Biotransformation Conjugates
Acetic acid……………………………………………… 11 mg 100 mg *
Glycine………………………………………………… 44 mg 400 mg *
Taurine………………………………………………… 56 mg 500 mg *
Trimethylglycine (TMG) HCl …………………………… 56 mg 500 mg *
N-Acetylcysteine (NAC)……………………………….. 22 mg 200 mg 10%
*Dietary Reference Intake not established. Sources: Tocopherols: soy. Tocotrienols: palm.
Other ingredients: <3% corn starch, gelatin, ~0.4% soy and vegetable oil, ~0.3% sucrose, silicon dioxide, calcium phosphate, maltodextrin, Acacia gum, ascorbyl palmitate, sorbitan monostearate, gum Arabic, < 0.003% coconut oil, dl-alpha tocopherol.
To your health!
AOR
#3
Posted 28 January 2005 - 06:39 PM
Nice formula!
Put Life Extension on notice to remove the niacinamide. Also, that is a generous dose of Sulforaphane, must be expensive.
I want to buy isolated Pyrroloquinoline quinone, you gonna sell it?
Put Life Extension on notice to remove the niacinamide. Also, that is a generous dose of Sulforaphane, must be expensive.
I want to buy isolated Pyrroloquinoline quinone, you gonna sell it?
#4
Posted 28 January 2005 - 10:08 PM
Quote
Vitamin A and BoNE
Concerns for Cancer Patients
Reports of increased bone fracture risk are a concern when higher potency vitamin A supplements are taken over the long-term (Michaelsson et al. 2003). One study showed bone mineral density was reduced by 10 percent in those taking more than 5000 IU of vitamin A from both dietary sources and supplements. This study showed that compared to lower intakes of vitamin A, those taking more than 5000 IU of vitamin A had a 2.1 time higher risk of hip fracture.
One reason people take vitamin A supplements is to reduce cancer risk. What these bone density/fracture studies fail to ascertain is whether the same people taking higher doses of vitamin A had lower incidences of cancer. These studies also fail to establish whether the study participants were taking adequate amounts of bone-protecting nutrients such as manganese, zinc, copper, vitamin K, and magnesium. It could be that people consuming lots of vitamin A-fortified milk and eating vitamin A-rich organ meats had deficiencies of other nutrients critical to bone maintenance. One of these nutrients is folic acid, which lowers homocysteine levels. Excess homocysteine participates in degenerative bone degradation.
From a practical standpoint, a healthy person is left with some unanswered questions. A plethora of published studies associates low vitamin A intake with increased cancer risk (see Reference list for Appendix A). Guarding against vitamin A deficiency is thus a critical component of a cancer prevention program. It would therefore appear practical to supplement with 5000 IU a day of vitamin A, but perhaps higher doses are not needed. In fact, taking higher doses of vitamin A over an extended time period without other bone-protecting nutrients would appear to increase fracture risk. Refer to the Osteoporosis protocol for complete details about the steps you can take to protect against the loss of bone mineral density and subsequent risk of fracture.
Concerns for Cancer Patients
Reports of increased bone fracture risk are a concern when higher potency vitamin A supplements are taken over the long-term (Michaelsson et al. 2003). One study showed bone mineral density was reduced by 10 percent in those taking more than 5000 IU of vitamin A from both dietary sources and supplements. This study showed that compared to lower intakes of vitamin A, those taking more than 5000 IU of vitamin A had a 2.1 time higher risk of hip fracture.
One reason people take vitamin A supplements is to reduce cancer risk. What these bone density/fracture studies fail to ascertain is whether the same people taking higher doses of vitamin A had lower incidences of cancer. These studies also fail to establish whether the study participants were taking adequate amounts of bone-protecting nutrients such as manganese, zinc, copper, vitamin K, and magnesium. It could be that people consuming lots of vitamin A-fortified milk and eating vitamin A-rich organ meats had deficiencies of other nutrients critical to bone maintenance. One of these nutrients is folic acid, which lowers homocysteine levels. Excess homocysteine participates in degenerative bone degradation.
From a practical standpoint, a healthy person is left with some unanswered questions. A plethora of published studies associates low vitamin A intake with increased cancer risk (see Reference list for Appendix A). Guarding against vitamin A deficiency is thus a critical component of a cancer prevention program. It would therefore appear practical to supplement with 5000 IU a day of vitamin A, but perhaps higher doses are not needed. In fact, taking higher doses of vitamin A over an extended time period without other bone-protecting nutrients would appear to increase fracture risk. Refer to the Osteoporosis protocol for complete details about the steps you can take to protect against the loss of bone mineral density and subsequent risk of fracture.
Life Extension's Super Booster contains mixed tocopherols, 10 additional mg of Lycopene delivered in an oil base among a list of many ingredients. Super Booster is strongly encouraged to Life Extension foundation members because Life Extension Mix is dry powder only.
Life Extention Mix can be purchased with high or low dose Niacin if one is concerned.
I believe it is ignorant to ignore Green Tea's ability to combat heart disease, cancer, tooth decay and arthritis.
So AORSupport, how much did you have to give ImmInst.org to peddle your products here? LOL! [lol]
#5
Posted 29 January 2005 - 08:48 AM
AORsupport, the one thing that confounds me everything I visit your website is the seemingly missing price and buy button. I must be missing something, but for the life of me I can't figure out how to buy anything.
?
?
#6
Posted 29 January 2005 - 09:04 AM
Nerve (is that you?),
Like many supplement suppliers, they do not sell direct to the public. The same would be true if you visited the website of Jarrow, twinlab....
For best prices try froogle for any AOR product.
Like many supplement suppliers, they do not sell direct to the public. The same would be true if you visited the website of Jarrow, twinlab....
For best prices try froogle for any AOR product.
#7
Posted 29 January 2005 - 02:05 PM
I agree, LEF tends to throw a bunch of stuff into their forumulations without really thinking about the interactions. AOR's forumulation looks much better.
#8
Posted 29 January 2005 - 05:09 PM
Quote
Possible side effects and precautions
Green tea, even in large amounts, is associated with very few side effects. In mice, signs of toxicity were only observed when doses reached 2 g/kg daily of an 80% polyphenol abstract (this is about the equivalent of 8 cups per pound of body weight, per day – 1200 cups of tea in a 150 lb. individual) [80].
It is possible that large amounts of polyphenols could impair mineral absorption, making extra mineral supplements a wise course of action. Of primary importance is a significant inhibition of nonheme iron absorption, which is relevant if most of your iron comes from sources other than meat [81, 82]. It is possible that there is also mild inhibition of calcium, manganese, and zinc [83, 84], although there is a study that disputes the finding of impaired zinc absorption [84]. The only place where the phenomenon of significant mineral blockage by green tea has even been of worry is in Tunisia, where there is high tea intake and non-meat products are the primary source of dietay iron [81]. However, it may be prudent to take a multivitamin supplement that provides adequate amounts of these minerals at a separate time or a low-dose slow release iron supplement if one decides to consume large amounts of polyphenols.
Green tea, even in large amounts, is associated with very few side effects. In mice, signs of toxicity were only observed when doses reached 2 g/kg daily of an 80% polyphenol abstract (this is about the equivalent of 8 cups per pound of body weight, per day – 1200 cups of tea in a 150 lb. individual) [80].
It is possible that large amounts of polyphenols could impair mineral absorption, making extra mineral supplements a wise course of action. Of primary importance is a significant inhibition of nonheme iron absorption, which is relevant if most of your iron comes from sources other than meat [81, 82]. It is possible that there is also mild inhibition of calcium, manganese, and zinc [83, 84], although there is a study that disputes the finding of impaired zinc absorption [84]. The only place where the phenomenon of significant mineral blockage by green tea has even been of worry is in Tunisia, where there is high tea intake and non-meat products are the primary source of dietay iron [81]. However, it may be prudent to take a multivitamin supplement that provides adequate amounts of these minerals at a separate time or a low-dose slow release iron supplement if one decides to consume large amounts of polyphenols.
Life Extension Mix does indeed have extra zinc and manganese in their formula.
Once again the overwhelming body of evidence states that green tea has significant health promoting effects.
#9
Posted 29 January 2005 - 08:47 PM
Wow. AOR great formula. Balanced nicely with the best forms and doses I've seen yet in a multi. I thought LEF's multi was good, but had flaws that along with the price kept me away. Looking forward to Ortho Core.
#10
Posted 29 January 2005 - 10:17 PM
Thank you, AOR, for the detailed and prompt response!
No doubt, - I will give Ortho-Core a try - - looks truly awesome and promising!
But that depends on the price naturally, as my resources are not limitless... :-\
What do you (AORsupport) think of Pharmanex's Lifepak (I'm currently using it) ?
Forever!
Daniel
No doubt, - I will give Ortho-Core a try - - looks truly awesome and promising!
But that depends on the price naturally, as my resources are not limitless... :-\
What do you (AORsupport) think of Pharmanex's Lifepak (I'm currently using it) ?
Forever!
Daniel
#11
Posted 30 January 2005 - 08:36 AM
scottl said:
Nerve (is that you?),
Like many supplement suppliers, they do not sell direct to the public. The same would be true if you visited the website of Jarrow, twinlab....
For best prices try froogle for any AOR product.
Like many supplement suppliers, they do not sell direct to the public. The same would be true if you visited the website of Jarrow, twinlab....
For best prices try froogle for any AOR product.
Thanks Scott, I hadn't realized they were only manufacturers.
#12
Posted 30 January 2005 - 10:40 AM
inarchunite said:
Thank you, AOR, for the detailed and prompt response!
No doubt, - I will give Ortho-Core a try - - looks truly awesome and promising!
But that depends on the price naturally, as my resources are not limitless... :-\
What do you (AORsupport) think of Pharmanex's Lifepak (I'm currently using it) ?
Forever!
Daniel
No doubt, - I will give Ortho-Core a try - - looks truly awesome and promising!
But that depends on the price naturally, as my resources are not limitless... :-\
What do you (AORsupport) think of Pharmanex's Lifepak (I'm currently using it) ?
Forever!
Daniel
Daniel,
I think that AORSupport gave some very good pointers in his message to possible problems with different MVs. I suggest you go through that list and see if anything is applicable to the MV you are using.
As for AOR OC, I can attest that cheap it is not. Maybe you should consider AOR's essential mix instead?
hope this helps,
Yosi
#13
Posted 30 January 2005 - 02:30 PM
Going over the AOR essential mix forumla again I notice a few things that might give me problems.
NAC for one, it makes me lose hair for some reason, also Indole-3-Carbinol.
Those are great anti-oxidants however both seem to make me lose hair. I have played extensively with supp's and have noticed that some make me prone to slight hair loss.
The NAC hairloss has been reported on usenet newsgroups as well, not sure about I-3-C but since it mucks with the testosterone/estrogren balance I believe that is what does it. It throws my system of of hormonal balance and seems to cause hairloss.
Just want to post this here so maybe you guys will take notice of this, as I dont think many vitamin manufacturers are aware there can be the problem of hairloss in prone individuals with these vitamins.
Probably most users dont realize it either unless they pay special attention to the supp's they take and their side effects.
NAC for one, it makes me lose hair for some reason, also Indole-3-Carbinol.
Those are great anti-oxidants however both seem to make me lose hair. I have played extensively with supp's and have noticed that some make me prone to slight hair loss.
The NAC hairloss has been reported on usenet newsgroups as well, not sure about I-3-C but since it mucks with the testosterone/estrogren balance I believe that is what does it. It throws my system of of hormonal balance and seems to cause hairloss.
Just want to post this here so maybe you guys will take notice of this, as I dont think many vitamin manufacturers are aware there can be the problem of hairloss in prone individuals with these vitamins.
Probably most users dont realize it either unless they pay special attention to the supp's they take and their side effects.
#14
Posted 30 January 2005 - 10:09 PM
The total dose of NAC is only 200mg which to me seems like just enough for benefit, while not nearly enough to cause any side effects. Remember that is with 9 caps/day so you could always take less. Just a thought.
#16
Posted 31 January 2005 - 08:06 AM
http://www.aor.ca/
elrond, on the left bar, the third box down it says "From Where to Buy". In that box you can "enter a city name or a postal code" and it lists the stores in your area.
elrond, on the left bar, the third box down it says "From Where to Buy". In that box you can "enter a city name or a postal code" and it lists the stores in your area.
#17
Posted 02 February 2005 - 02:57 AM
Hi,
I'm tempted to buy it from this Canadian supplier: http://www.globalvitamins.ca/product%20cat...%20page%202.htm
what do you think?
I'm tempted to buy it from this Canadian supplier: http://www.globalvitamins.ca/product%20cat...%20page%202.htm
what do you think?
#18
Posted 02 February 2005 - 05:35 AM
cosmos said:
http://www.aor.ca/
elrond, on the left bar, the third box down it says "From Where to Buy". In that box you can "enter a city name or a postal code" and it lists the stores in your area.
elrond, on the left bar, the third box down it says "From Where to Buy". In that box you can "enter a city name or a postal code" and it lists the stores in your area.
Been there, done that. Couldn't find a US supplier. Even the websites it listed didn't actually have it on their order pages when I clicked through and looked around.
Share this topic:
1 User(s) are reading this topic
0 members, 1 guests, 0 anonymous users
Loading