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Nutraceuticals promote stem cell proliferation


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#1 resveratrol

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Posted 26 September 2007 - 08:07 PM


Forgive me if this has been posted before, but the latest issue of LE Magazine had an article that I found rather fascinating, specifically pointing to a synergistic effect for blueberry, green tea, vitamin D3, carnosine, and catechin in stimulating hematopoietic stem cells.

The scientists in this study used GM-CSF as a positive control from which to evaluate the stem cell-promoting effects of various nutrient combinations. As expected, GM-CSF increased bone marrow cell proliferation by around 46%, which was better than any single nutrient compound tested.43

When combinations of nutrients were tested, however, a greater percentage of bone marrow cell proliferation occurred compared to GM-CSF. For example, a combination of blueberry and vitamin D3 exhibited a 62% increase in proliferation of bone marrow cells.43 Blueberry and catechin (green tea extract) increased bone marrow cell proliferation by 70%. When carnosine and blueberry were combined, the growth promotion observed was 83% . . . an effect significantly greater than that of the expensive drug GM-CSF!43
Green tea leaves

The scientists next tested various nutrients on early stem cells, which can be identified and isolated by their surface antigen-receptor expressions (e.g., CD34 + and CD 133 +). The GM-CSF drug increased these early stem cells by 48%, as expected. A combination of blueberry, green tea, vitamin D3, and carnosine, however, increased these stem cells by an astounding 68%.


The LEF article is here:

http://www.lef.org/m...006_awsi_01.htm

The full paper referred to in that segment of the LE article is available here (login and purchase required):

http://www.lieberton...scd.2006.15.118

Edited by resveratrol, 26 September 2007 - 08:25 PM.





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