43 replies to this topic

[steelsky]

Melitor is the name of the product in Ukraine. pharmacy1010 have it in their catalog but is sold out. It sounds to be really promising with no side effects! Almost too good to be true. There is some reviews on dr-bob.org of people that have been in a trial.

It costs A LOT! Any cheaper source? :(

[curtis]

An anxiolytic antidepressant would be a better option than a benzodiazepine on a long-term basis. You might want to check out agomelatine, which is brand new drug from Servier that fits the bill with an entirely novel mechanism of action. It was recently approved in the EU and is available by mail order from Europe.

Agomelatine/Valdoxan is a VERY interesting new antidepressant. I myself are on the "waiting list" for this drug. I am now taking 40 mg Lexapro/Cipralex after a rebound depression - before i were on 10 mg.

Agomelatine/Valdoxan has been approved by EU, but it also has to be approved by every country before it can be marketed. Here in Denmark it were approved approx. 1-2 months after EU, and the latest I have heard is that it will be available in May. I don't think it can be bought anywhere right now!?

Jackinbox: I would say that Lexapro have helped me alot through the last 4-5 years, with no noticeable side effects. However as you can see it kinda stoppped working suddenly - but remember that you might be reacting different on the drug. I have never made a withdrawal from Lexapro so I can't comment on this, but I have heard it can be quite horrendous. As a matter of fact that's the main reason I have stayed on this drug for so many years - I have tried the "brain zaps" and it's the worst thing I have EVER experienced. That reason alone should be enough for you to wait and try agomelatine/valdoxan as it shouldnt have the SSRI withdrawal symptoms. But they said the same when the SSRI started hitting the market, we will know a lot more in the coming years i guess.

If i should recommend something in the meanwhile it would be pure EPA - fish oil with the DHA removed.

[curtis]

An anxiolytic antidepressant would be a better option than a benzodiazepine on a long-term basis. You might want to check out agomelatine, which is brand new drug from Servier that fits the bill with an entirely novel mechanism of action. It was recently approved in the EU and is available by mail order from Europe.

Agomelatine/Valdoxan is a VERY interesting new antidepressant. I myself are on the "waiting list" for this drug. I am now taking 40 mg Lexapro/Cipralex after a rebound depression - before i were on 10 mg.

Agomelatine/Valdoxan has been approved by EU, but it also has to be approved by every country before it can be marketed. Here in Denmark it were approved approx. 1-2 months after EU, and the latest I have heard is that it will be available in May. I don't think it can be bought anywhere right now!?

Jackinbox: I would say that Lexapro have helped me alot through the last 4-5 years, with no noticeable side effects. However as you can see it kinda stoppped working suddenly - but remember that you might be reacting different on the drug. I have never made a withdrawal from Lexapro so I can't comment on this, but I have heard it can be quite horrendous. As a matter of fact that's the main reason I have stayed on this drug for so many years - I have tried the "brain zaps" and it's the worst thing I have EVER experienced. That reason alone should be enough for you to wait and try agomelatine/valdoxan as it shouldnt have the SSRI withdrawal symptoms. But they said the same when the SSRI started hitting the market, we will know a lot more in the coming years i guess.

If i should recommend something in the meanwhile it would be pure EPA - fish oil with the DHA removed.

[LET ME GET EM!]

As with any psychological issue it would be best to first seek out the underlying problem via rehtorical questioning. And/or if one has experienced the issue before consuming any prescriptions and are still experiencing those issues... then quit those prescriptions all together and start with the first advice of questioning oneself with hard, foundation-shattering fully honest questions in regards to YOUR CURRENT situation and mindstate. Of course you have asked for advice and advice is what you will recieve, but on an honest note... most have suffered from anxiety due to them being mentally and physically OUT OF CONTROL. You must take control.

With Love,

Alex(Brandon)

[k10]

Go on Google Groups and search for "Agomelatine Psychonauts" if you are interested in discussion with current users of the drug. They also have more information there on how to obtain it.

Have you received/tried it yet funk?

[FunkOdyssey]

Yes, its just sitting around though. My mom was going to use it and chickened out. I haven't decided if I will experiment with it yet.

[solracselbor]

I have a masters degree in psychology with a concentration in Positive Moods and Mood Pathologies. I will be recieving my Ph.D upon completion of my current program.

There is increasing evidence that there is no such thing as a "chemical imbalance", chemicals in the brain fluctuate depending on your current mood. All the drugs in the world will do nothing for you but provide a short term placebo effect that will decrease your anxiety for a short period of time. I can tell you with utmost confidence that the best way to relenquish yourself of anxiety is to simply reorganize your thought process. Are you anxious about being anxious? Do you get anxious about things that may not statistically probable? Ask your self these things in order to find the underlying problem and answer it. My best advice for you, without giving you a course of therapy, would be to simply stop fighting any urge of anxiety. You need to let the anxiety "wash over you". By trying to stop the anxiety, you increase it. Just let the anxiety "wash over you" and in a short period of time you will train your body to no longer respond in the same manner; in this way future feelings of anxiety will be reduced to normal levels.

[Phreak]

I have a masters degree in psychology with a concentration in Positive Moods and Mood Pathologies. I will be recieving my Ph.D upon completion of my current program.

There is increasing evidence that there is no such thing as a "chemical imbalance", chemicals in the brain fluctuate depending on your current mood. All the drugs in the world will do nothing for you but provide a short term placebo effect that will decrease your anxiety for a short period of time. I can tell you with utmost confidence that the best way to relenquish yourself of anxiety is to simply reorganize your thought process. Are you anxious about being anxious? Do you get anxious about things that may not statistically probable? Ask your self these things in order to find the underlying problem and answer it. My best advice for you, without giving you a course of therapy, would be to simply stop fighting any urge of anxiety. You need to let the anxiety "wash over you". By trying to stop the anxiety, you increase it. Just let the anxiety "wash over you" and in a short period of time you will train your body to no longer respond in the same manner; in this way future feelings of anxiety will be reduced to normal levels.

I started writing a reply but got carried away.
SEE:

Handling Your Psychological Problems - "My 2 Cents"

Phreak

Edited by Phreak, 07 May 2009 - 09:57 PM.

[FunkOdyssey]

I don't like that reductionist theory of anxiety either, as it entirely ignores a plethora of well-documented physiological causes. I have experienced anxiety as a manifestation of Lyme Disease -- it turns out that antibiotics resolve this anxiety far more effectively than "letting the anxiety wash over me". And if you experience anxiety caused by hyperthyroidism, how effective is "reorganizing your thought processes" going to be?

Its all in your head... except when it is not.

[Phreak]

I don't like that reductionist theory of anxiety either, as it entirely ignores a plethora of well-documented physiological causes. I have experienced anxiety as a manifestation of Lyme Disease -- it turns out that antibiotics resolve this anxiety far more effectively than "letting the anxiety wash over me". And if you experience anxiety caused by hyperthyroidism, how effective is "reorganizing your thought processes" going to be?

Exactly. It kind of seems like your trying to write-off or ignore clinically proving medical problems by saying that our brain chemistry differs from person to person, and the chemical neurotransmitters fluctuate. Well... yeah It's beyond reductionist, it's borderline eliminativist!

Its all in your head... except when it is not.

I like this

[piet10]

Agomelatine works great but is also very bad for the stomach and intestines, it has a very burning flavour which many stomachs just cant handle so be carefull with it.

[How.I.Met.Me]

Avoid SSRI at all cost... Try glutamine and inositol. Whey protein also calms you down. And make sure to rule out possiblity of infection. Your sinus, throat, ear and eyes are good indication of possible brain infection.

[e Volution]

I don't like that reductionist theory of anxiety either, as it entirely ignores a plethora of well-documented physiological causes. I have experienced anxiety as a manifestation of Lyme Disease -- it turns out that antibiotics resolve this anxiety far more effectively than "letting the anxiety wash over me". And if you experience anxiety caused by hyperthyroidism, how effective is "reorganizing your thought processes" going to be?

Exactly. It kind of seems like your trying to write-off or ignore clinically proving medical problems by saying that our brain chemistry differs from person to person, and the chemical neurotransmitters fluctuate. Well... yeah It's beyond reductionist, it's borderline eliminativist!

Its all in your head... except when it is not.

I like this

Very interesting stuff, this is a great debate for a newbie like me... What would your guys response be to individuals who experienced anxiety in the past (including debilitating anxiety for decades) and 'trained' themselves out of it through therapy or drastic life changes, etc? What would be a scientific explanation for what has happened in their brain in these circumstances? And why is that not potentially applicable to everyone (outside of more prominent but lower probability reasons like disease and such)?

Also, that link from Phreak is broken and I would really like to read it, anyone help?

[madanthony]

I have been getting more aware of my anxiety issues recently and I think it I should try to do something about it. The problem with anxiety medications is that it generally make people feel tired and that's something I cannot afford. I also worry about side effects.

I'm thinking of trying a benzo for a while since I would be able to know quite fast how much anxiety is an issue for me.

It seems that Lexapro is the SSRI with the less side effect and some positive effect on anxiety. It might be an option but I'm not sure I want to go thru the build-up period that might last a few weeks.

Do you have any advice for me?

By the way, I tried phenibut and theanine. Theanine is great for sleep but my stomach can't handle it.

Don't throw anything at m, but I will give you the treatments that have worked for anxiety for DOGS:

(1) In the early days of the internet I had a dog with really bad anxiety and also some sort of arthritis. A nutritionist on the web told me to try brewer's Yeast for the dog...that the main protein in it is glutamate and if taken with no other proteins it would cross the BBB and improve mood - she said they do it to the psyciatric patients at some institution she wokred at twice/day to good effect. It worked for my dog and the dog's arthritis improved 90% also. I don't think it was normal arthritis -- the dog's neck would lock to the side and it would make walking straight difficult. The dog never had that problem again.
(2) Later I had a dog with anxiety problems including auch a bad fear of thumder she could not stop shking even when I held her. I gave her melatonin and she would smile. She would run to me for her melatonin. Of course that made her sleepy so she would go to a dog park and just lay there and smile. So I took her to an alternative vet and the vet perscribed B100's 2/day for her (a 45 pound beagle). The vet said it would take 2-6 weeks to "build up" in her system and be effective. Since B vitamins are water soluble and don't "build up" I can only conclude the time delay is time to clear out things like homocysteine. In 2 weeks she had no fear of thunder and her other anxiety symptoms disappeared also. I took another larger do (75 pounds) for the same problem and the same dose was prescribed.


that's a large dose for a little dog. I only take half that and have considered that maybe I should take more myself.