65 replies to this topic

[DukeNukem]

Top 12 General Supplements for the New Year

Ortho-Core
http://www.aor.ca/re.../ortho_core.php

Ortho-Mind
http://www.aor.ca/pr.../ortho_mind.php

CoQ10 (Ubiquinol)
http://www.lef.org/n.../item00952.html

Vitamin C with Dihydroquercetin
http://www.lef.org/n.../item00981.html

Fish Oil (EPA/DHA)
http://www.lef.org/n.../item00902.html

SODzyme
http://www.lef.org/n.../item00961.html

Resveratrol
https://www.gonsi.co...ku-835003006373

Blueberry Extract Capsules w/Pomegranate
http://www.lef.org/n.../item00938.html

LycoPom (includes pomegranate)
http://tinyurl.com/yjpmg5

Green & White Tea
http://tinyurl.com/yanjw3

PhenCarLE (contains Algaebrium a.k.a. generic ALT-711)
https://www.lenutri.com/order/#

Melatonin (one hour before bed time)
http://www.lef.org/n.../item00546.html


A few notes:

o Ortho-Core covers all of the basic bases, including all 8 vitimers of E, vitamin K2 (critical for bone regeneration), and all the basic minerals. A basic vitamin/mineral formula is needed to feed 1000's of required chemical reactions inside the body.

o Ortho-Mind likewise feeds and protects chemical processes within our most vital organ.

o Dihydroquercetin, a key component of the vitamin C supplement, appears to be a super booster for vitamin C, helping it re-circulate throughout the body and remain effective longer. As a bonus, dihydroquercetin itself inhibits lipid peroxidation, a process that leads to atherosclerosis (hardening of the arteries). Dihydroquercetin is also an anti-inflammatory, it protects red and white blood cells, and it destroys two of the three most dangerous free radicals, superoxide and peroxide radicals.
http://www.lef.org/m...vitaminc_01.htm

o Ubiquinol appears to be the most potent new form of CoQ10, and also has a significantly longer life with the body than previous versions of CoQ10.
http://tinyurl.com/yjx4wx

o The resveratrol recommendation will quickly be a moving target, I'm sure. It's easy to predict that more potent resveratrol supplements will soon appear, given all the recent news & excitement.

o Pomegranate is a miracle-class plant supplement (alongside three other resveratrol, green/white tea and blueberry). Anything that can reduce arterial place by 35% a year is a must-take supplement -- plus it helps prevent cancer. (I include two sources, to ensure getting enough.)
http://tinyurl.com/ylectb

o Blueberry is also a profoundly beneficial supplement (thanks to its unique polyphenol, pterostilbene, a close cousin to resveratrol), yet to get its due. It has many of the benefits of pomegranate and resveratrol, plus it crosses the blood-brain barrier and is highly protective of the brain.

o SODzyme has been shown to extend life in mice, and effectively elevates levels of one of the body's most critical free radical fighters (free radicals are a leading cause of aging and disease).

o Algaebrium is one of the first in a new class of glycation breakers, and has been shown to significantly relax the vascular system, lowering blood pressure. It likely has the same effect on most organs. A true anti-aging drug.
http://morelife.org/...ms/ALT-711.html

o Melatonin has multiple high-level benefits, not the least of which is greatly improving the quality of sleep, thus allowing the body to better self-repair. It's also a powerful anti-oxidant that crosses the blood-brain barrier. Research shows that mice live 40% longer with continued use. Excellent fully referenced review of melatonin on Medscape at:
http://www.medscape....e/472385?src=mp

o Nature has given us several of what I half-jokingly call "miracle-class supplements," such as the four I mention above: resveratrol (from grapes and knotweed), pterostilbene (from blueberries), epigallocatechin-3-gallate and co-factors (from green/white tea), and punicalagins (from pomegranate). Until nanotech comes to the rescue, it is doubtful that we'll come across natural supplements that are more beneficial to the body, and likewise safe, too. These miracle-class supplements provide profound protection against heart & vascular disease, brain dysfunction, and cancer.

o This list is in no way complete (my personal regimen includes dozens of additional supplements), but it's the kind of foundation that can make a significant difference, assuming it is not sabotaged by poor food intake.

o If I had to add an additional supplement, I'd add AOR's R-Lipoic Acid. (Although, some is included in Ortho-Mind.) http://www.aor.ca/products/r+sr.php. Next I'd add some sort of glucose management supplement stack, such as http://www.aor.ca/re...tho_glucose.php

o For all supplements, take as recommended by the manufacturer. Except, I recommend no less than three vitamin C capsules daily (morning, afternoon, bedtime).

Edited by dukenukem, 20 December 2006 - 06:34 PM.

[FunkOdyssey]

There isn't any R-Lipoic Acid in Ortho-Core, unless they snuck that in when I wasn't looking. That's a good list though, thanks Duke [thumb]

SodZyme I do have some resverations about, re: how effective it would really be in humans.

I would think benfotiamine and pyridoxamine are worthy of a place on this list for their potent inhibition of AGE's, and Aged Garlic should be up there with EGCG, blueberry, and any of the other "miracle" natural food products.

[health_nutty]

Thanks for the list.

I agree with you about Pomegranate, the preliminary human research is amazing. I think it is very underrated here on imminst.
I too am surprised Aged Garlic Extract is not on the list.
ALT-711 seems very promising, but is to early in the research (and expensive) for me to take the plunge. Maybe if I was older and richer

[Athanasios]

Indeed, thanks Duke.

Funk, I think he meant Ortho-Mind.

[curious_sle]

Duke, i largely agree but would like to support FunkOdyssey in stressing the importance (to me in the "indispensable" list) of pyridoxamin and benfotiamin. What i am weary of is LEnutri. I wouldn't want to buy from them even though i really really would like to get stuff like alt-711 or mito-q (mitoVit-E and some related stuff too :-) ).

I for one hope for decent cost effective resveratrol supplements, if possible as mixed blend redwine extract.

[DukeNukem]

Here's the garlic I take:
http://www.puritypro...2K55A350E4X48K2

As much as I like garlic, I don't see the research that tells me it should be considered in the league of blueberry, resveratrol, pomegranate and green tea. It seems to be one notch below. Same with Turmeric, another favorite of mine.

>>> pyridoxamin and benfotiamin...

These are definitely in my next group. The idea with this first group is to cover the best bases that lead to better health and life-extension. I picked the low hanging fruit first, and next I would start to branch out into more specific areas that cover glucose management (a massively important area), AGE's management, inflammation management, nootropics, and so on.

As for LENutri, I agree this is a shaky supplier, but for now I'm somewhat trusting, having had a few emails exchanges with the owner. He seems to be the only public seller of generic ALT-711.

[Shepard]

I would probably swap SODzyme for NAC, but it looks pretty good.

[Pablo M]

Nothing new here, just LEF magazine Cliff Notes and some gonzo megasupplement hype. Add in some alkalized water, coral calcium and colloidal silver and now we've got a stack!

[Athanasios]

Here is a thread where many others put their top 10 supplements, be welcome to add or update yours here:

http://www.imminst.o...t=0#entry130812

[Centurion]

Green tea, resveratrol, pomegranate + basic multi. A good strong foundation for now while I'm a student. Once I start earning ill look into the others.

[DukeNukem]

Nothing new here, just LEF magazine Cliff Notes and some gonzo megasupplement hype

.
Not sure why you think that. Only half the supps come from LEF, and that's because they are very often on the very cutting-edge, such as with the CoQ10 and their Vitamin C with dihydroquercetin. I also favor AOR products for the same reason. We are lucky to have supplement makers who are quick to market with supplements based on new research.

[mitkat]

Add in some alkalized water, coral calcium and colloidal silver and now we've got a stack!

LOL!

[scottl]

Thanks for posting your list Duke. Though I really need to add for the uninformed....


"As for LENutri, I agree this is a shaky supplier"

This is an understatement--Mike Rizzer AKA smi2le??

See thread here:

http://www.avantlabs...30

And zillions of complains all over the web and in older threads here.

[boily]

Thanks Duke for the list, awesome! Appreciate you sharing your ideas, research and links!

[spins]

Add in some alkalized water, coral calcium and colloidal silver and now we've got a stack!

LOL!

Oh man, that was funny! [lol]

[kenj]

I echo the Ortho-Mind. This is a brilliant "beginners choice", including KEY potent nutrients for brain health and thus superior mental stamina, - everything I've read re: protecting yourself against accelerating cognitive decline and Alzheimer's, point to supplementing exactly with some of the compounds found in Ortho-Mind.
I can testify OM's effectiveness in my own brain having taken it for few months last year, - at present I take Acetyl-L-Carnitine and R-Lipoic Acid on empty stomach every morning, CDP-Choline and a standardized Ginkgo Biloba leaf extract w/breakfast every other day, as part of my brain nutritional, free radical fighting, triple protecting program.

[mitkat]

My only reservation with the list is the one item in ortho-mind I refuse to take at my age:

Huperzine-A (from 20 mg Huperzia serrata 0.5%) .. 100 mcg

Other than that.... lookin' well nice

[biknut]

o Algaebrium is one of the first in a new class of glycation breakers, and has been shown to significantly relax the vascular system, lowering blood pressure. It likely has the same effect on most organs. A true anti-aging drug.

Never heard of this one. Sounds interesting to me. Could this help with high blood pressure?

Can anyone elaborate about its benefits?

[Shepard]

Just Google ALT-711, you'll get a nice MoreLife link, a blog entry at FuturePundit, some discussion on the LEF forums, a Fight Aging! entry, etc.

[biknut]

Just Google ALT-711, you'll get a nice MoreLife link, a blog entry at FuturePundit, some discussion on the LEF forums, a Fight Aging! entry, etc.

Thanks shepard.

[caston]

I had a Pomegranate tree at my old house when I was a kid.

[DukeNukem]

>>> Could this help with high blood pressure?

Big time. It seems that everyone whom takes generic ALT-711 (a.k.a. Alagebrium) benefits from significant BP improvement. In effect, when broken, these protein-glucose bindings have the effect of relaxing all organs, including the skin. Fight Aging has a pretty good recent write-up:
http://www.fightagin...ives/000981.php

Note that Alagebrium doesn't unlock all types of glycation bindings, but some is better than none, and more drugs are coming that will tackle the others.

[biknut]

Thanks duke, that's very interesting reading. If no one knows of any reason why I shouldn't give this a try I'm going to order some.

[kenj]

re: hup-A in OM its an inhibitor of acetylcholinesterase, and IMO the best herb at providing "nootropic effects". I don't know if it's really an age-related concern, given breaks taken in the supplement, also if dosing at 2-4 caps/day.
When checking, even non-5-HTP-appreciating LEF carry a hup-A 50mcg product.

[xanadu]

Would anyone care to comment on the comparison between alt-711 and benfotiamine? It sounds like they do similar things just by reading the literature. Benfotiamine has been researched longer and does not seem to have the side effects of the other. Or am I oversimplifying?

[mitkat]

re: hup-A in OM its an inhibitor of acetylcholinesterase]herb[/i] at providing "nootropic effects". I don't know if it's really an age-related concern, given breaks taken in the supplement, also if dosing at 2-4 caps/day.
When checking, even non-5-HTP-appreciating LEF carry a hup-A 50mcg product.

I have never taken hup-a before, nor do I plan to anytime soon...I've read a number of papers that show it in a less than favourable light in the past. There were a few threads discussing this, I thought at least someone agreed with me...?

[curious_sle]

Would anyone care to comment on the comparison between alt-711 and benfotiamine? It sounds like they do similar things just by reading the literature. Benfotiamine has been researched longer and does not seem to have the side effects of the other. Or am I oversimplifying?

AFAIR benfotiamine inhibts crosslink formation whereas alagebrium breaks some (one?) types of formed crosslinks.

[DukeNukem]

>>> Would anyone care to comment on the comparison between alt-711 and benfotiamine? <<<

Yeah, there are many AGE inhibitors that prevent glycation, but only one glycation breaker that actually reverses damage that's been done. We definitely need more breakers available to us -- they are hugely important.

Edited by dukenukem, 12 December 2006 - 04:14 PM.

[xanadu]

Yeah, there are many AGE inhibitors that prevent glycation, but only one glycation breaker that actually reverses damage that's been done. We definitely need more breakers available to us -- they are hugely important.

But what about the side effects of the "breaker"? That's what I'm worried about. The side effects may be worse than the damage it undoes. The saying about an oz of prevention being better than a lb of cure is very true. Is there any evidence of animals or humans living longer because of alt-711?

[DukeNukem]

Xanadu,

I am very careful about the non-natural supps I take, such as Deprenyl, Metformin, and Alagebrium. For the latter, there have been people taking it for 5 years, and have only seen positive benefits. Alteon's website indicates this is a very safe supp, when used properly.

I suggest you google "ALT-711" and read the top entry. It very thoroughly goes through the safety in's-and-out's of this drug.

I've been using it for nearly a year. So far, thumbs up. Tangible benefits. In fact, last week I increased my dosage by 50%.