• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

first ever attempt at nootropics


  • Please log in to reply
18 replies to this topic

#1 dave31

  • Guest
  • 9 posts
  • 0

Posted 19 June 2007 - 10:23 AM


ok i only found out about nootropics abot 3 weeks ago and hae done abit research into the matter and have ordered the following; alpha gpc choline,acetyl l carnitine,aniracetam,ashwagandha,bacopa,centrophenoxine,chorline bitartrate,deprenyl liquid,idebenone,ginkgo biloba,krill oil,l-arginine,melatonin,modafinil,phenibut,piracetram,PEA,pyritinol,sulbutiamine and vinocentine.

the l-arginine,deprenyl, centrophenoxine chorline bitartrate and pyritinol has come, i had taken them all separately but am now on all 3 at the same time, i first took the liquid deprenyl (hard to say what th dose was as the dropper that came with it didnt have any markers on but i guess it was around 3-5mg)for 4 days before i took the other 2 and noticed that i got alot more things done in the day and was tired much later in the day and as i drive for 11 hours a day this was a welcome effect.
next i took the pyritinol(400mg) about 3 hours before i took the centro, it was a little disappointing as i didnt really feel any different apart from abit of brain fog which wasnt what i bought it for! anyway the centro was then taken(500mg) and apart from the stomach ache i got from taking it on a empty stomach it completely woke me up and make me very alert, centro is best for me so far.
the reason i am posting this is because i have ordered alot of drugs and i may have not researched enough and would like opinions on the above drugs as a complete stack(i.e. are there any drugs in that stack that cannont be taken together for health reasons etc etc) apart from the PEA,phenibut,sulbutiamine which would be cycled round to order, i am also thinking of ordering galantamine resvertol,pramiracetam,picamilon,rasagiline,ritalin and rhodiola as well.

i would like to add that i am also on dustastiride(0.5mg daily) and cycle round clomid,noladex and ferma.

thanks in advance dave.

Edited by dave31, 20 June 2007 - 09:07 AM.


#2

  • Lurker
  • 0

Posted 19 June 2007 - 06:15 PM

That's a lot of drugs. The krill oil and herbs are not a big concern. But I'd go real slow with the drugs - adding them one at a time. Probably centro (or alpha gpc choline) and one of the 'racetrams is a good place to start.

Also, there is some evidence which indicates that pyritnol may cause liver damage in some people. Also, studies have shown that idebenone may cause electron leakage in some circumstances which is not so good.

Don't be surprised if you end up throwing some of that stuff out. I think this is an experience many of us have gone through. Also, use the search function on PubMed - lots of useful information there.

sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#3 luv2increase

  • Guest
  • 2,529 posts
  • 37
  • Location:Ohio

Posted 19 June 2007 - 10:45 PM

Too much stuff. Do you have bad anxiety? Why do you want to cycle phenibut? What are you expecting off the PEA? Why the clomid and nolvadex? Are you ending a steroid cycle? I'm just trying to get a clue as to why there are so much stuff and the reasons for some of them.


Also, studies have shown that idebenone may cause electron leakage in some circumstances which is not so good.


Where?

#4 ksperfection

  • Guest
  • 28 posts
  • 0

Posted 20 June 2007 - 02:04 AM

Geez thats a ton to get at once. All I can say is add some of them slowly to get a good idea of if their worth the money and try changing the dosages as well if your not getting good results. Im not familar with most of those, but I doubt there are serious reactions caused by taking 2 of them combined together, though it is quite likely that your body won't react well to atleast 1 of those products.

As Noots are synergetic the dosages you'll need of each will decrease as you take more of them (especially for similar ones like the racetams) as you go along adding more you might find yourself feeling lously from taking 1 more but that may not be caused by that aloen but having too high combination of all your drugs.

Since you've already bought these products its unlikely you won't try them after doing some research (atleast I wouldnt). I'd research it by simply searching through this site's search function for a particular drug to see what people say and use google to find research reports or others exerpeinces. The purprose of this would be to figure out which ones you want to try next, as it could take you months and months to phase each one in.

#5 shifter

  • Guest
  • 716 posts
  • 5

Posted 20 June 2007 - 07:33 AM

You will definatly start noticing something when you take the PEA after the deprenyl. Haven't had any experience with the other stuff.

You have to be very careful with certain supplements and drugs while on MAO inhibitors. You dont have to be so careful with certain foods if you are taking low doses of Deprenyl though but who knows with the other supps/drugs you have put into the mix. Might be hard to research the exact combo you have taken all around the same time.



The PEA is not something I would take every day to get you through though. Take a little for when your going out for a good social time. Not to get through a boring mundane day at work.

#6 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 20 June 2007 - 09:21 AM

thanks for the repleys, the other drugs have not come yet, i will be phasing all the drugs in 1 by 1 to see how i get on with them and base my stack around the results.
the reason im taking these is purely to act as a cog enhancer and for more energy though out the day to get things done, im very lazy see and need a kick up the backside!
the clomid, nolvadex are there to stop the bitch tits i get from the dustastiride, this seems to be quiet a common problem as i know at least 5 ppl who suffer from the same side effects.
centro i feel is working the best at moment, i have tried it without the others and it does work, the pyritinol im not so sure about doesnt seem to have much of a effect on me, yesterday while taking these i posted a new high for me on that site lumosity.com, i use the raindrops test and scored 11400, my prevous best was 8200, that is quiet a leap.
anyway waiting for these others drugs to turn up and will let u lot know how i get on, cheers.

#7 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 21 June 2007 - 05:51 PM

hd a chance to do some more research today and will be changing l-arginine to aakg and will be adding resveratol.

#8 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 27 June 2007 - 05:24 PM

ok got a few of the drugs now and have set out this stack but it is changing daily as i shuffle things around and try new things:

1 hour before breakfast-
aakg-3g
chorline bit- 600mg

with breakfast-

krill oil-500mg
fish oil-1000mg
centrophenoxine-500mg
chorline bit-600mg
deprenyl-5mg
pyritinol-200mg
vit c-1200mg
dustastiride- 0.5mg
clomid-100mg
vinpocentine-10mg
alcar-600mg
resveratol-100mg

lunch(about 4,5 hours later)

krill oil-500mg
fish oil-1000mg
centrophenoxine-250mg
pyritnol-200mg
chorline bit- 600mg
vinpocentine-10mg
alcar-600mg

dinner( 4 to 6 hours later)

prritnol-200mg
alcar-600mg

1 hour to 30 mins before bed

aakg-3g
alcar-600mg
ashwagandha(8% win) 225mg( this only came today so havent used this yet)


20 mins before bed

melatonin-3mg( this doesnt seem to work very well and just got my 5mg tabs today so will be changing to those.

so what u all think for far? i know its far from finished but i havent got the rest yet and will lower dosages on certain things when other stuff come.

#9 trevyn

  • Guest
  • 87 posts
  • 43

Posted 27 June 2007 - 05:34 PM

Some people find lower doses of melatonin to work better than higher doses. I prefer about 1-1.5mg, and I'm a good 200lbs.

Ritalin? Are you ADHD, or looking for something to compare the modafinil to? I haven't tried either, but if you're looking for a stimulant, I'm quite enjoying my phenylpiracetam at the moment.

I also agree that you should slow down a little bit, and give yourself time to figure out the effects of individual substances on your body. I know it's exciting to have all this cool stuff available, but it helps to be able to identify what specifically gives you a boost, or causes an unwanted reaction. A lot of life extension supplements are taken "on faith" without immediately observable effects, but I think that to warrant continued consumption, you should notice specific improvements from individual nootropics.

#10 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 28 June 2007 - 01:45 PM

my bloodpressure has gone through the roof and i need to find out why quickly, can u look at the above stack and maybe come up with some sugestions, cheers.

bp before stack 105/80

today resting bp same as before 153/91!!

#11 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 28 June 2007 - 01:54 PM

just done some reading, do u think it might be that i drink about 3-4 strong coffees a day? also my deprenyl is selegline liquid and i thinki read somewhere that u dont need 5mg of that as its more bioavailable? might be completely wrong, havent had a look at any of the other drugs yet, im abit worried as i have never had high bp.

#12 synaesthetic

  • Guest
  • 230 posts
  • 0
  • Location:San Diego

Posted 28 June 2007 - 03:55 PM

I recommend starting off with only .5mg - 1mg deprenyl... I'd be wired and full of anxiety if I did 5mg liquid + 3-4 coffees... Maybe try switching over to green tea, the L-theanine in it might help.

#13 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 28 June 2007 - 05:03 PM

just read on pubmed that selegiline might not as specific as first thought for moa type b inhibitor and might inhibit type a,as well , if that is the case what should i do? reduce to 1mg daily, reduce to 1-2mg every other day, or 1-5mg weekly? or give it up totally? also what other drugs would affect this now in light of this new info?

cheers

Edited by dave31, 28 June 2007 - 06:08 PM.


#14 luv2increase

  • Guest
  • 2,529 posts
  • 37
  • Location:Ohio

Posted 28 June 2007 - 07:38 PM

First of all, while it has nothing to do with moa a & b inhibition, how old are you?

Try 1-2mg a day and see how that goes.

#15 shifter

  • Guest
  • 716 posts
  • 5

Posted 28 June 2007 - 11:24 PM

It starts to lose its selectivity at doses at around 20+mg per day. None of us would ever need 10+mg so I would never go near that even. Depending on what you want to use it for 5mg would be a good maximum for ordinary healthy people.

I've been taking 5mg selegiline every day and blood pressure is normal. (when not on pea :) ) Feelings are normal, and diet still contains cheeses and other tyramine containing foods.

resveratrol is an inhibitor of p450 right?. And when on medication doctors sometimes warn about grapefruit juice (as that inhibits p450). I'm wondering how that affects the deprenyl. I have stopped taking the pomegrante and resveratrol extracts, but I did take it once when I noticed the odd blood pressure readings (but am sure that was due to the PEA anyway and did not test before without the pomeratrol pill). If your worried about blood pressure and want to take PEA than take only minute doses..... :)

#16 dave31

  • Topic Starter
  • Guest
  • 9 posts
  • 0

Posted 29 June 2007 - 08:30 AM

im 31 and in good shape and never had a problem in my life with bp, anyway i took another reading today 20 mins after i got up and before nearly all the drugs for the day except for aakg 3g ad chorline bit 600mg which i took 15 min before reading bp and it was 118/64 which is alot better but i still want it down abit.
today i will not be taking any deprenyl to see if this has any effect on it, i didnt know anything about the resveratol effecting bp, there might be something in that as i doubled the res dose yesterday to 200mg, also i forgot to mention that i tried PEA the afternoon before, i took about 100-200mg cant be sure cas it was by teaspoon but would that still effect the bp about 30 hours later?

as a side note ive been taking 5mg melatonin and ashwangandha 225mg (8%) before bed and have over 10.5 hours both nights, i normally sleep 8-9 and i still knackered in the morning, but i dont know if its th drugs or the fact that ive just started gym again and my bodys killing all over.

#17 shifter

  • Guest
  • 716 posts
  • 5

Posted 29 June 2007 - 01:49 PM

I dont think resveratol affects blood pressure as such but wonder what the effects are with mixing it with medication.

Blood pressure rising is pretty short lived from PEA in my experience.

#18

  • Lurker
  • 0

Posted 29 June 2007 - 02:57 PM

im 31 and in good shape and never had a problem in my life with bp, anyway i took another reading today 20 mins after i got up and before nearly all the drugs for the day except for aakg 3g ad chorline bit 600mg which i took 15 min before reading bp and it was 118/64 which is alot better but i still want it down abit.
today i will not be taking any deprenyl to see if this has any effect on it, i didnt know anything about the resveratol effecting bp, there might be something in that as i doubled the res dose yesterday to 200mg, also i forgot to mention that i tried PEA the afternoon before, i took about 100-200mg cant be sure cas it was by teaspoon but would that still effect the bp about 30 hours later?

as a side note ive been taking 5mg melatonin and ashwangandha 225mg (8%) before bed and have over 10.5 hours both nights, i normally sleep 8-9 and i still knackered  in the morning, but i dont know if its th drugs or the fact that ive just started gym again and my bodys killing all over.


I think to balance your neurotransmitters properly you have to focus on the inhibitory ones first. When you get the inhibitory neurotransmitters under control THEN you add the things that have a stimulating effect like deprenyl.

Otherwise you could run into some problems with anxiety or impulsivity issues or OCD issues or perhaps problems with blood pressure.

Inhibitory neuros are GABA, serotonin, glycine and taurine. And I happen to think that taurine can help to balance the other inhibitory neuros.

sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#19 kiwigeezer

  • Guest
  • 3 posts
  • 0

Posted 11 July 2007 - 09:32 AM

Jesus 100mg of Clomid a day I would not recommend if you value your eyesight.




2 user(s) are reading this topic

0 members, 2 guests, 0 anonymous users