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Does inderal has negative effects on the function


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#1 ariobarzan

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Posted 02 October 2007 - 07:16 AM


Does inderal has negative effects on the function of brain?
Inderal is used for treating ADD this Drug reduce the heart rate and therefore the blood pressure.
I think reducing of blood pressure can reduce the brain cells nutrition (some nootropics work with increasing the blood flow in the Brain) it seems that these two agents work against each other!
If it is true What can I do for treating ADD with out this effect ?

#2 rebuild101

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Posted 02 October 2007 - 12:06 PM

As I understand it, you don't have much to worry about. Blood flow and blood pressure don't seem to be the same thing in regards to cognition -- or at least in this study:

http://in.news.yahoo.../139/6lb77.html

"It was found that taking either antihypertensive medication actually increased the inefficiency of the brain's work during memory."

Maybe someone else can provide more detailed information. Of course, if your trying to improve blood flow, you can use some mild to moderate exercise, too. If you don't like inderal, ask your doctor about TENEX (generic: guanfacine) or other options. I'm actually in the same boat as you with regards to anti-hypertension.

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#3 dehbleh

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Posted 02 October 2007 - 10:39 PM

I was taking the beta-blocker metoprolorol for a period of up to 8 months and at the time I didn't realise why but I was getting increasingly worse mood swings, particularly at the end of a working day. Turns out I have hypoglycemia (which I always suspected) and beta-blockers not only mask the physical aspects of a low blood sugar episode (sweating, palpatations etc) but they can also cause your sugar levels to drop even lower. Hypoglycemia can really destroy your brain if you don't take care of it and at times, on this medication, I was having psychotic episodes at least once a week. And don't get me started on the nightmares and sleep-walking it caused....

#4 Futurist1000

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Posted 02 October 2007 - 11:15 PM

I was taking the beta-blocker metoprolorol for a period of up to 8 months and at the time I didn't realise why but I was getting increasingly worse mood swings, particularly at the end of a working day.

Beta blockers sometimes have depression as a side effect. It may also be because they block noradrenergic receptors that are involved in mood. Drugs that increase norepinephrine usually can improve mood, so if you block some of those receptors your mood could take a turn for the worst.

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#5 dehbleh

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Posted 03 October 2007 - 11:03 PM

Beta blockers sometimes have depression as a side effect.  It may also be because they block noradrenergic receptors that are involved in mood.  Drugs that increase norepinephrine usually can improve mood, so if you block some of those receptors your mood could take a turn for the worst.


I defintely felt almost a dulling sense in my excitability, so for quite awhile it felt unnatural. But that was not really the problem, hypoglycemia was. I was prone to it before hand but whilst on metoprolorol I just couldn't stop the levels from dropping towards the end of the day. It messed with me in a huge way.

If anyone has suffered really bad hypoglycemia you'll know it starts off with the littlest of things ticking you off. This then progresses to a state of confusion, coordination becomes impaired (driving like someone who is mildly intoxicated) and a deep irritable scatteredness sets in. At times it feels like a really harsh MDMA come down, everything seems to annoy the shit out of you no matter how much you try to rationalise the situation. Also, your pupils become dilated the more your body's physical stress manifests itself. In the midst of all this your brain is getting damaged to a considerable (and I believe totally overlooked) extent.

I am still so surprised that today many physicians find "hypoglycemia" a debatable topic. Dumbarses...




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