Wait wait, are you telling me the pure extract of polypodium leucotomos is different to the polypodium leucotomos extract that is in heliocare?
No. But I don´t know if they´re the same. That is why I´m using Heliocare.
Edit: And where do Artichoke extract and coffee come in to it? Aren't we talking about Heliocare? And isn't the main active polypodium leucotomos?
The main active in Heliocare is Polypodium leucotomos extract (PL). But the main active phenolics in PL is ferulic, vanillic, p-coumaric, caffeic and chlorogenic acids. These phenolics can also be found in other extracts beside Polypodium Leucotomos. For example in artichoke and coffee.
Polypodium leucotomos extract: antioxidant activity and disposition. Gombau L,
García F,
Lahoz A,
Fabre M,
Roda-Navarro P,
Majano P,
Alonso-Lebrero JL,
Pivel JP,
Castell JV,
Gómez-Lechon MJ,
González S. Advancell, 46009 Valencia, Spain.
The extract of the fern Polypodium leucotomos (PL, Fernblock) is an oral photoprotectant with strong antioxidative properties.
Recent studies to determine its chemical composition have shown 4-hydroxycinnamic acid (p-coumaric), 3 methoxy-4-hydroxycinnamic acid (
ferulic), 3,4-dihydroxycinnamic acid (
caffeic), 3-methoxy-4-hydroxybenzoic acid (
vanillic) and 3-caffeoilquinic acid (
chlorogenic)
to be among its major phenolic components. No conclusive data are available, however, on the H2O2-scavenging capacity of these compounds, or on their absorption and metabolism following their oral intake. In the present work, their antioxidative capacity was assessed by the luminol/H2O2 assay, their absorption studied using Caco-2 cells to resemble the intestinal barrier, and their metabolism investigated using cultured primary rat hepatocytes. The antioxidant capacity of PL components increased in a concentration-dependent manner, with ferulic and caffeic acids the most powerful antioxidants. The apparent permeability results correspond to a human post-oral administration absorption of 70-100% for all tested substances. Coumaric, ferulic and vanillic acids were metabolized by CYP450-dependent mono-oxygenases and partially conjugated to glucuronic acid and sulfate. These phenolic compounds may contribute to the health benefits afforded by this oral photoprotectant.
PMID: 16263237 [PubMed - indexed for MEDLINE]
Edited by Fredrik, 02 July 2008 - 04:30 AM.