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Adderall synergy?


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#1 lucidver

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Posted 14 March 2009 - 06:46 AM


I am just curious if there is anything that synergizes with Adderall (besides caffiene/nicotine)

Thanks =)

#2 mentatpsi

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Posted 14 March 2009 - 09:31 AM

i'm currently interested in trying to see the synergy with theanine. I think caffeine and Adderall is a poor combination, mainly since it seems to increase habitual behaviors, but it's good if you're doing repetitive work. Theanine seems like it might take out the extreme wired quality to adderall.

Another eventual experimentation will be Idebenone with it.

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#3 lucidver

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Posted 14 March 2009 - 09:03 PM

What is the correlation with Adderall and Ph levels? I read here that its efficiency is decreased if your Ph is too acidy?

#4 mentatpsi

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Posted 18 March 2009 - 02:19 AM

quick note:

Idebenone & Adderall might not be a safe combination, not entirely sure of this. I mainly state this because Idebenone seems to increase norepinephrine and the contradictions of Adderall spoke of MAOI's, pointing directly to norepinehphrine and other associated neurotransmitters. I know the mechanism of action is most likely different, and most likely the cause for this warning is associated with the mechanism of action of MAOI and how they could create an unhealthy amount of norepinephrine.

I wanted to let people know of this so that they wouldn't try experimenting with the compound alongside. I'm going to assume MAOI procedures for moving between the two. As in give somewhere close to a week before taking one or the other. If anyone knows anything else do make mention. Sorry to switch the topic.

There is a correlation to pH levels and the effectiveness of adderall:
"Alkalinity increases bioavailability and acidity causes the drug to be excreted sooner. Manufacturers claim that the mixture of salts in Adderall XR makes its effects smoother (that is, makes softer highs and lows); however, there is little support for this claim." Adderall: Chemistry

#5 DJS

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Posted 18 March 2009 - 03:33 AM

I am just curious if there is anything that synergizes with Adderall (besides caffiene/nicotine)

Thanks =)


Personally, I consciously avoided caffiene while on adderall. There is a big difference between "synergy" and overstimulation.

I think the whole idea of trying for synergy with adderall is a bit dangerous. It's a powerful amphetamine that should "do the job" on its own.

If you're not getting the desired effect it's possible that you're building up tolerance. If so, I'd recommend taking breaks from it on weekends (or whenever you can afford less than optimal focus).

Also, I've read conversations about using two tsps of Delsym daily (which contains DXM) to inhibit tolerance build up. Google "delsym" "adderall" and "tolerance" and you'll probably find some conversations.

#6 bgwithadd

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Posted 18 March 2009 - 04:57 AM

Make sure to take plenty of magnesium, but not at the exact same time. Acidity affects how well it's absorbed so don't take it with orange juice. Taking it with food, especially a bit of bread, will give the best absorbtion. Aside from taking memantine all the ways to potentiate adderall are either dangerous (well, more dangerous), unhelpful, or both. I do take it with deprenyl, but it does not seem to make it more effective - it does make the dopamine level side effects higher, though, but that's not really a good thing. IE, I can normally sleep well on adderall but when I first took it with deprenyl it took about a week before I could sleep much.

#7 mentatpsi

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Posted 18 March 2009 - 05:46 AM

Make sure to take plenty of magnesium, but not at the exact same time. Acidity affects how well it's absorbed so don't take it with orange juice. Taking it with food, especially a bit of bread, will give the best absorbtion. Aside from taking memantine all the ways to potentiate adderall are either dangerous (well, more dangerous), unhelpful, or both. I do take it with deprenyl, but it does not seem to make it more effective - it does make the dopamine level side effects higher, though, but that's not really a good thing. IE, I can normally sleep well on adderall but when I first took it with deprenyl it took about a week before I could sleep much.


Are you sure the deprenyl and adderall is a good idea?

#8 Cuil

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Posted 18 March 2009 - 01:54 PM

American spirits (a brand of cigarettes) will help with increasing focus on stimulants. Don't mix caffiene with adderall. It may extend some of its wakefullness effects, but its also more likely to disrupt concentration if you are sleep deprived. Atleast in my case, where I drank some tea to increase the effects of adderall and I guess I

Edited by Cuil, 18 March 2009 - 02:08 PM.


#9 mentatpsi

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Posted 18 March 2009 - 05:40 PM

American spirits (a brand of cigarettes) will help with increasing focus on stimulants. Don't mix caffiene with adderall. It may extend some of its wakefullness effects, but its also more likely to disrupt concentration if you are sleep deprived. Atleast in my case, where I drank some tea to increase the effects of adderall and I guess I


tea's effects in comparison to caffeine are quite different. I posted a research article on it [Caffeine & Theanine].
Have you blended the two together in conditions other than sleep deprivation?

#10 Zosimos

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Posted 18 March 2009 - 05:45 PM

I am just curious if there is anything that synergizes with Adderall (besides caffiene/nicotine)

Thanks =)


Personally, I consciously avoided caffiene while on adderall. There is a big difference between "synergy" and overstimulation.

I think the whole idea of trying for synergy with adderall is a bit dangerous. It's a powerful amphetamine that should "do the job" on its own.

If you're not getting the desired effect it's possible that you're building up tolerance. If so, I'd recommend taking breaks from it on weekends (or whenever you can afford less than optimal focus).

Also, I've read conversations about using two tsps of Delsym daily (which contains DXM) to inhibit tolerance build up. Google "delsym" "adderall" and "tolerance" and you'll probably find some conversations.


These conversations do indeed exist... However they have zero basis in fact (or at the very least neither evidence nor rationalizations were provided). Irregardless, I would advise you to be cautious of anyone who suggests incorporating a highly addictive cough syrup into your regimen.

Edited by Zosimos, 18 March 2009 - 05:47 PM.


#11 FunkOdyssey

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Posted 18 March 2009 - 05:55 PM

memantine is much safer than DXM for that purpose -- DXM is an ugly, dirty drug.

#12 lucidver

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Posted 19 March 2009 - 03:21 AM

> "I think the whole idea of trying for synergy with adderall is a bit dangerous. It's a powerful amphetamine that should "do the job" on its own."

In high school, I took 10mg, 3 times a day, and later that went up to 15mg, 20mg, and finally 25mg, 3 times a day.

After high school I quit, but have had difficult focusing for a long, long time. My reasons were partly financial and partly moral.

I recently started on Adderall XR 10mg, which is just a 1 a day thing, a dose which is probably less than ideal for my body weight, but chosen purposely to keep Adderall at a minimum, as it would seem that I really do have terrible ADD and that a low dosage of amphetamine does help quite a lot with that.

The reason why I'd like a "synergy" is to be able to sustain taking only the 10mg for longer without having to bump up 20mg. I am looking for some focus outside of Adderall so that I don't have to become completely reliant on it, and, also that I can take breaks and keep the dosage low instead of having it continuously amped up every six months when it starts to become inefficient and unusable, which was the case in the past.

In other words, I am looking for the desired focus with as little Adderall as possible for as long as possible.

I am also exercising and eating very well.

Cheers =)

Edited by lucidver, 19 March 2009 - 03:35 AM.


#13 luv2increase

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Posted 19 March 2009 - 07:05 PM

I took prescribed adderall once about a year and a half or so ago for about a month, and I can attest that it does not go well with any nootropics which I've tried. I've tried about all of them as well except for pramiracetam, phenylpiracetam, pyritinol, galantamine, hydergine, & tianeptine. The latter two I am using now with astounding success, but I never mixed them with adderall.

#14 bgwithadd

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Posted 19 March 2009 - 09:11 PM

Make sure to take plenty of magnesium, but not at the exact same time. Acidity affects how well it's absorbed so don't take it with orange juice. Taking it with food, especially a bit of bread, will give the best absorbtion. Aside from taking memantine all the ways to potentiate adderall are either dangerous (well, more dangerous), unhelpful, or both. I do take it with deprenyl, but it does not seem to make it more effective - it does make the dopamine level side effects higher, though, but that's not really a good thing. IE, I can normally sleep well on adderall but when I first took it with deprenyl it took about a week before I could sleep much.


Are you sure the deprenyl and adderall is a good idea?


It says right on the label not to. I'd not recommend it to anyone but I seem ok with low levels of each, at least.

#15 PowerfulP

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Posted 19 April 2015 - 06:56 AM

I found adderall + tianeptine to be a good combo. Just feels smooth and I feel I can handle everything with a sense of calm. Also with caffeine + l-theanine thrown in.

 

Memantine daily for adderall tolerance. Although it has not stopped the tolerance like I was hoping, based on so many anecdotal reports. 

 

A good alternative to adderall for me has been PEA + selegilene. Very similar effect. This may be a risky combo though, so I don't necessarily advocate it. 


Edited by PowerfulP, 19 April 2015 - 06:57 AM.


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#16 TiredAt45

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Posted 18 May 2015 - 06:21 AM

I found adderall + tianeptine to be a good combo. Just feels smooth and I feel I can handle everything with a sense of calm. Also with caffeine + l-theanine thrown in.

 

Memantine daily for adderall tolerance. Although it has not stopped the tolerance like I was hoping, based on so many anecdotal reports.

 

I'm finding as well that tianeptine is taking away the grumpy irritability that I suffered from before amph., and which has been exacerbated on it.

 

I take only 1-2 doses of 12.5mg tianeptine each day (weighed on a proper 60.00000g resolution analytical balance ;-)






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