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Mortality lowest at 22.5-25.0 BMI - study of 900,00 adults


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#1 Brett Black

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Posted 22 July 2010 - 04:14 AM


Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
http://www.ncbi.nlm....les/PMC2662372/

"In both sexes, mortality was lowest at about 22·5–25 kg/m2. Above this range, positive associations were recorded for several specific causes and inverse associations for none, the absolute excess risks for higher BMI and smoking were roughly additive, and each 5 kg/m2 higher BMI was on average associated with about 30% higher overall mortality"

"Below the range 22·5–25 kg/m2, BMI was associated inversely with overall mortality, mainly because of strong inverse associations with respiratory disease and lung cancer. These inverse associations were much stronger for smokers than for non-smokers, despite cigarette consumption per smoker varying little with BMI."

"If the overall inverse association at low BMI is partly non-causal, then the real optimum BMI might be somewhat lower than the apparent optimum of about 23 kg/m2 or 24 kg/m2."

"The definite excess mortality below 22·5 kg/m2 is due mainly to smoking-related diseases, and is not fully explained."

(note: figure 6 shows increased mortality below a BMI of 22.5 even amongst those who have never smoked regularly)

Edited by Brett Black, 22 July 2010 - 04:15 AM.


#2 Guest

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Posted 22 July 2010 - 07:11 PM

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
http://www.ncbi.nlm....les/PMC2662372/

"In both sexes, mortality was lowest at about 22·5–25 kg/m2. Above this range, positive associations were recorded for several specific causes and inverse associations for none, the absolute excess risks for higher BMI and smoking were roughly additive, and each 5 kg/m2 higher BMI was on average associated with about 30% higher overall mortality"

"Below the range 22·5–25 kg/m2, BMI was associated inversely with overall mortality, mainly because of strong inverse associations with respiratory disease and lung cancer. These inverse associations were much stronger for smokers than for non-smokers, despite cigarette consumption per smoker varying little with BMI."

"If the overall inverse association at low BMI is partly non-causal, then the real optimum BMI might be somewhat lower than the apparent optimum of about 23 kg/m2 or 24 kg/m2."

"The definite excess mortality below 22·5 kg/m2 is due mainly to smoking-related diseases, and is not fully explained."

(note: figure 6 shows increased mortality below a BMI of 22.5 even amongst those who have never smoked regularly)


It appears s if you intend to imply something. I do not want to second guess your potential concerns about the higher mortality among the 1000nds of caloric restriction with optimal nutrition guys in that study. Obviously, there is no other cohort of people that could fall into a low-BMI category.




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